BDBM50576715 CHEMBL4870282

SMILES CN(CCCN1c2ccccc2CCc2ccccc12)C(=O)CCCCCNC(=O)C[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=HZUAHAJHTJHMBK-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50576715   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
The University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576715(CHEMBL4870282)
Affinity DataIC50: 1.83E+5nMAssay Description:Inhibition of human recombinant SIRT5 assessed as inhibition of substrate desuccinylation using Fluor de Lys-Succinyl green peptide as substrate in p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
The University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576715(CHEMBL4870282)
Affinity DataKd:  2.47E+3nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT5 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
The University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576715(CHEMBL4870282)
Affinity DataKi:  1.22E+5nMAssay Description:Inhibition of human recombinant SIRT5 assessed as inhibition of substrate desuccinylation using Fluor de Lys-Succinyl green peptide as substrate in p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed