BDBM50576578 CHEMBL4871074

SMILES Oc1c(Br)cccc1CNc1ccc2nc3CCCn3c(=O)c2c1

InChI Key InChIKey=XNIIZXAGWLPTRZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50576578   

TargetAcetylcholinesterase(Electric eel)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50576578(CHEMBL4871074)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by addition of substrate and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50576578(CHEMBL4871074)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by addition of substrate and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50576578(CHEMBL4871074)
Affinity DataIC50: 8.34E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation measured after 48 hrs by ThT flourescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed