BDBM50575029 CHEMBL4864604
SMILES CC(=O)N1Cc2cc(ccc2[C@@H]1C(=O)Nc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(C)(=O)=O
InChI Key InChIKey=QYYZXEPEVBXNNA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50575029
Affinity DataIC50: 41nMAssay Description:Inverse agonist activity at human RORC2 assessed as inhibition of SRC1-derived coactivator peptide by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inverse agonist activity at human RORC ligand binding domain incubated for 30 mins by scintillation proximity binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inverse agonist activity at mouse RORC ligand binding domain incubated for 30 mins by scintillation proximity binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human RORA assessed as recruitment of PGC1alpha (130 to 154) coactivator peptide by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human RORB assessed as recruitment of PGC1alpha (130 to 154) coactivator peptide by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human RORgamma by TR-FRET assayMore data for this Ligand-Target Pair