BDBM50574280 CHEMBL4853030

SMILES CNC[C@@H](Nc1nc(nc2c(cccc12)C(N)=O)C(F)(F)F)c1cccc(F)c1

InChI Key InChIKey=GDZSUVPAQIUIGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50574280   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574280(CHEMBL4853030)
Affinity DataIC50: 400nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574280(CHEMBL4853030)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed