BDBM50573690 CHEMBL4855590

SMILES CN(CCNc1ccc2ncc(-c3ccc(cc3)C(N)=O)n2n1)C(=O)OC(C)(C)C

InChI Key InChIKey=YNQNYIHMAZLJAV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50573690   

TargetAP2-associated protein kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573690(CHEMBL4855590)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAP2-associated protein kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573690(CHEMBL4855590)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of recombinant human GST-Xa-tagged-AAK1 (30 to 330 residues) expressed in baculovirus expression system using (5 -FAM)-Aha-KEEQSQITSQVTGQI...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAP2-associated protein kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573690(CHEMBL4855590)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of recombinant AAK1 (unknown origin) expressed in baculovirus assessed as reduction in AP-2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAP2-associated protein kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50573690(CHEMBL4855590)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of recombinant AAK1 expressed in human HEK293F cells co-expressed with AP-2 assessed as reduction in AP-2 phosphorylation by western blott...More data for this Ligand-Target Pair
In DepthDetails
PubMed