BDBM50573584 CHEMBL4845782

SMILES COc1cc(ccc1CN1CC(C1)C(O)=O)-c1cccc(c1C)-c1cccc(c1C)-c1ccc(CN2CC(C2)C(O)=O)c(OC)c1

InChI Key InChIKey=GGYAWQLTANAFTB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573584   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573584(CHEMBL4845782)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of Tag2-PD1/Tag1-PD-L1 (unknown origin) protein-protein interaction preincubated for 15 mins followed by addition of anti-Tag1-Eu3+ and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573584(CHEMBL4845782)
Affinity DataEC50:  104nMAssay Description:Inhibition of PD1/PDL1 protein-protein interaction in human Jurkat cells overexpressing PD1 co-cultured with human Hep3B cells expressing PDL1 protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed