BDBM50572783 CHEMBL4866486

SMILES CCC(C)NC(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=WFUIXHLNJVJPQY-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50572783   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50572783(CHEMBL4866486)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to MMSET (973 to 1203 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50572783(CHEMBL4866486)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of NSD2 (953 to 1240 residues) (unknown origin) using SAM as substrate in presence of nucleosome by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed