BDBM50572203 CHEMBL4855172

SMILES COc1ccc2nccc(CCN3CCC(CC3)NCc3ccc(Cl)cn3)c2n1

InChI Key InChIKey=BMANDSXMIVZGEY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50572203   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50572203(CHEMBL4855172)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50572203(CHEMBL4855172)
Affinity DataIC50: 123nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50572203(CHEMBL4855172)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed