BDBM50571129 CHEMBL4862733

SMILES OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C1=C(C2CC(C1O2)S(=O)(=O)N(Cc1ccccc1)CC(F)(F)F)c1ccc(O)cc1

InChI Key InChIKey=LPRWMOJRYCIJTB-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50571129   

TargetEstrogen receptor beta(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50571129(CHEMBL4862733)
Affinity DataEC50:  102nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50571129(CHEMBL4862733)
Affinity DataKi:  554nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50571129(CHEMBL4862733)
Affinity DataKi:  1.55E+3nMAssay Description:Binding affinity to human ERbeta LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed