BDBM50571114 CHEMBL4871032

SMILES CN(c1cccc2ccccc12)S(=O)(=O)C1CC2OC1C(=C2c1ccc(O)cc1)c1ccc(NC(=O)CCCCCCC(O)=O)cc1

InChI Key InChIKey=YGCSFYKMJPJLIE-UHFFFAOYSA-N

Data  2 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50571114   

TargetEstrogen receptor beta(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50571114(CHEMBL4871032)
Affinity DataEC50:  6.51E+3nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50571114(CHEMBL4871032)
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of human recombinant HDAC8 incubated for 15 mins by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50571114(CHEMBL4871032)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human recombinant HDAC6 incubated for 15 mins by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50571114(CHEMBL4871032)
Affinity DataKi:  1.72E+3nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50571114(CHEMBL4871032)
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity to human ERbeta LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed