BDBM50571054 CHEMBL4864898

SMILES Cn1nc(Cc2nnc(SCCCCCCCC(=O)Nc3ccc(Cl)cc3Cl)n2CCC(O)=O)c2ccccc2c1=O

InChI Key InChIKey=APRYGLLMCLFANI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571054   

TargetInterleukin-15(Mouse)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50571054(CHEMBL4864898)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of RLI incubated for 30 mins followed by RLI addition and ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-15(Mouse)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50571054(CHEMBL4864898)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of IL2 incubated for 30 mins followed by IL2 addition and ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-15(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50571054(CHEMBL4864898)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-2(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50571054(CHEMBL4864898)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of IL2-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by al...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed