BDBM50571040 CHEMBL4867872

SMILES CCOC(CCn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCC(=O)Nc1ccc(Cl)cc1Cl)OCC

InChI Key InChIKey=PBCQBGMZGHYFPR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571040   

TargetInterleukin-15(Mouse)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50571040(CHEMBL4867872)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of RLI incubated for 30 mins followed by RLI addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetInterleukin-15(Mouse)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50571040(CHEMBL4867872)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of IL2 incubated for 30 mins followed by IL2 addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetInterleukin-15(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50571040(CHEMBL4867872)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetInterleukin-2(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50571040(CHEMBL4867872)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IL2-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed