BDBM50570566 CHEMBL4849604

SMILES COC(=O)C(=N/Nc1ccc(OC)cc1)\C(=O)C(F)(F)C(F)(F)C(F)(F)F

InChI Key InChIKey=IHRHACRFXNFJBN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50570566   

TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50570566(CHEMBL4849604)
Affinity DataIC50: 103nMAssay Description:Inhibition of porcine liver carboxylesterase using 4-NPA as substrate preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50570566(CHEMBL4849604)
Affinity DataIC50: 111nMAssay Description:Inhibition of human recombinant CES1 expressed in baculovirus infected BTI insect cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50570566(CHEMBL4849604)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed