BDBM50570357 CHEMBL4865147

SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccc(NC(=O)CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NCCCCC(=O)Nc8ccc9N%10C(=O)C[C@]%11([H])OCC=C%12CN%13CC[C@@]%14(c9c8)[C@]%13([H])C[C@]%12([H])[C@]%11([H])[C@]%10%14[H])cc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H]

InChI Key InChIKey=MQMVLFAEBALNCN-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50570357   

TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50570357(CHEMBL4865147)
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50570357(CHEMBL4865147)
Affinity DataIC50: 4.27E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1/beta(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50570357(CHEMBL4865147)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1/beta(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50570357(CHEMBL4865147)
Affinity DataIC50: 1.78E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50570357(CHEMBL4865147)
Affinity DataIC50: 1.34E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the onset of compound app...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50570357(CHEMBL4865147)
Affinity DataIC50: 55nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the later state of compou...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50570357(CHEMBL4865147)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranes preincubated for 30 mins followed by [3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed