BDBM50570171 CHEMBL4870713

SMILES OC(=O)c1cccc(NC(=O)c2ccc(OCc3ccccc3)cc2)c1

InChI Key InChIKey=UUFRLZFNBOCDER-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570171   

TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570171(CHEMBL4870713)
Affinity DataEC50:  135nMAssay Description:Agonist activity at FXR-LBD (unknown origin) assessed by ligand binding ability incubated for 3 hrs in absence of light measured by TR-FRET Coactivat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570171(CHEMBL4870713)
Affinity DataEC50:  9.10nMAssay Description:Agonist activity at FXR in human HeLa cells by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed