BDBM50569835 CHEMBL4850917

SMILES COc1ccc2c(NC3CCN(Cc4ccccc4)CC3)nc(NCCNC(=O)CCCCC(=O)NO)nc2c1

InChI Key InChIKey=DBBLWZNNVCFABF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50569835   

TargetHistone deacetylase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50569835(CHEMBL4850917)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of HDAC in human K562 cells using Boc-K(Ac)-AMC as substrate preincubated for 3 hrs followed by substrate addition and measured after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50569835(CHEMBL4850917)
Affinity DataIC50: 7.14E+3nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as effect on H3K9Me2 levels incubated for 48 hrs by immunofluorescence in-cell western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50569835(CHEMBL4850917)
Affinity DataIC50: 7.14E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569835(CHEMBL4850917)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of HDAC in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569835(CHEMBL4850917)
Affinity DataIC50: 5.73E+3nMAssay Description:Inhibition of HDAC in human K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed