BDBM50568938 CHEMBL4867467

SMILES Cn1c2nc(Nc3cccc(c3)S(C)(=O)=O)ncc2cc(-c2ccc(O)cc2)c1=O

InChI Key InChIKey=YISXPUJRNVVHRT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568938   

TargetActivin receptor type-1(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50568938(CHEMBL4867467)
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50568938(CHEMBL4867467)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed