BDBM50568523 CHEMBL4875015

SMILES Cl.Cn1cc(cn1)C(=O)Nc1ccc(cc1)[C@@H]1C[C@H]1NCC1CC1

InChI Key InChIKey=XYFPAGOQZFSLFH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50568523   

TargetLysine-specific histone demethylase 1A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568523(CHEMBL4875015)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal His-SUMO tagged human LSD1 (172 to 852 residues) expressed in Escherichia coli BL21 (DE3) using ART(mK)QTARKSTGGKAPRKQLAGGK-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetREST corepressor 1(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568523(CHEMBL4875015)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal His-SUMO tagged human LSD1 (172 to 852 residues)/His-tagged CoREST (286 to 482 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568523(CHEMBL4875015)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568523(CHEMBL4875015)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed