BDBM50568521 CHEMBL4878787

SMILES N[C@H]1CCN(C1)C(=O)CNC1CC1c1cc(F)cc(F)c1OCc1ccccc1

InChI Key InChIKey=CKUYVNUTAMQXJN-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50568521   

TargetLysine-specific histone demethylase 1A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568521(CHEMBL4878787)
Affinity DataKi:  560nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568521(CHEMBL4878787)
Affinity DataKi:  560nMAssay Description:Inhibition of LSD1 (unknown origin) assessed as inhibition constant by peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50568521(CHEMBL4878787)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of MAO-B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50568521(CHEMBL4878787)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibition of MAO-A (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 2(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568521(CHEMBL4878787)
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of LSD2 (unknown origin) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50568521(CHEMBL4878787)
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells using tyramine as substrate incubated for 30 mins by peroxidase-coupled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50568521(CHEMBL4878787)
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of human MAO-B expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate incubated for 30 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 2(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568521(CHEMBL4878787)
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of LSD2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed