BDBM50565632 CHEMBL4789906

SMILES Cn1cc(cn1)-c1cc2c(Nc3ccc(CC(=O)Nc4cc(nn4C)C(C)(C)C)cc3)ncnc2[nH]1

InChI Key InChIKey=JYNPEWRXWQEJMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50565632   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50565632(CHEMBL4789906)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human GST-tagged RET cytoplasmic domain (658 to 1114 residues) expressed in baculovirus expression system using 5-FAM-EEPLY...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50565632(CHEMBL4789906)
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant human N-terminal GST-HIS6 fused RET V804M mutant (658 to 1114 residues) expressed in Sf9 insect cells using 5-FAM-EEPLYWSFP...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed