BDBM50565180 CHEMBL4776204

SMILES NC(=N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](C(N)=O)c1ccccc1

InChI Key InChIKey=VREKBHVPVINEDT-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50565180   

TargetNeuropeptide FF receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human NPFFR1 expressed in CHO-K1 cells assessed as reversal of agonist-induced inhibition of forskolin-stimulated cAMP accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Affinity DataIC50: 387nMAssay Description:Antagonist activity at human NPFFR2 expressed in CHO-K1 cells assessed as reversal of agonist-induced inhibition of forskolin-stimulated cAMP accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Affinity DataKi:  58nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Affinity DataKi:  255nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Mouse)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Affinity DataKi:  824nMAssay Description:Displacement of [125I]-1DMeNPFF from mouse NPFF2R receptor by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-Kp-10 from human Kiss1 receptor by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-Diprenorphine from human DOP receptor expressed in HEK293 cells by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed