BDBM50565141 CHEMBL4779194

SMILES COc1cc2c(Nc3cccc(Br)c3)ncnc2cc1OCCCOC(=O)CCSSCC=C

InChI Key InChIKey=WISOXVRWVHHVTF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50565141   

TargetEpidermal growth factor receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50565141(CHEMBL4779194)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type EGFR in human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viabilit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50565141(CHEMBL4779194)
Affinity DataIC50: 7.31E+3nMAssay Description:Inhibition of wild type EGFR in human MCF7 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viability...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50565141(CHEMBL4779194)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type EGFR in human HT-29 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viabilit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50565141(CHEMBL4779194)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of wild type EGFR in human A-431 cells assessed as cell growth inhibition measured after 72 hrs by Celltiter-Glo luminescent cell viabilit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed