BDBM50564158 CHEMBL4794022

SMILES OC(=O)c1cccc2C3C(Cl)C(CC3C(Nc12)c1cccc(Br)c1)Sc1ccccc1[N+]([O-])=O

InChI Key InChIKey=XAXWAUYMIPGHTD-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50564158   

TargetDual specificity protein phosphatase 3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50564158(CHEMBL4794022)
Affinity DataIC50: 5.69E+4nMAssay Description:Inhibition of VHR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50564158(CHEMBL4794022)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of N-terminal His-tagged striatal-enriched protein tyrosine phosphatase (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50564158(CHEMBL4794022)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of LYP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50564158(CHEMBL4794022)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50564158(CHEMBL4794022)
Affinity DataIC50: 4.82E+4nMAssay Description:Inhibition of HEPTP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProtein phosphatase 1B(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50564158(CHEMBL4794022)
Affinity DataIC50: 1.65E+5nMAssay Description:Inhibition of PPM1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProtein phosphatase 1G(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50564158(CHEMBL4794022)
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of PPM1G (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase O(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50564158(CHEMBL4794022)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of GLEEP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50564158(CHEMBL4794022)
Affinity DataKi:  5.40E+3nMAssay Description:Competitive inhibition of N-terminal His-tagged striatal-enriched protein tyrosine phosphatase (unknown origin) assessed as inhibition of p-nitrophen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed