BDBM50563895 CHEMBL4784000

SMILES COc1cc(NC(=O)Nc2cc(on2)C(C)(C)C)ccc1Nc1ncnc2NCCOc12

InChI Key InChIKey=XWKBEUKRCQPJPK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50563895   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50563895(CHEMBL4784000)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human RET V804L mutant using KKKVSRSGLYRSP as substrate incubated for 15 mins followed by Mg/ATP addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50563895(CHEMBL4784000)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human RET V804M mutant using KKKVSRSGLYRSP as substrate incubated for 15 mins followed by Mg/ATP addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50563895(CHEMBL4784000)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human RET using KKKSPGEYVNIEFG as substrate incubated for 15 mins followed by Mg/ATP addition and measured after 40 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed