BDBM50563249 CHEMBL4741551

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nccc(\C(C)=C\C(=O)N(C)CCO)c2c1

InChI Key InChIKey=PBPMRYYZVXMZIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563249   

LigandPNGBDBM50563249(CHEMBL4741551)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiaxing University

Curated by ChEMBL
LigandPNGBDBM50563249(CHEMBL4741551)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end amino acids) using ULight-4E-BP1 as substrate incubated for 1 hr by LANCE Ul...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed