BDBM50562666 CHEMBL4758787

SMILES O=c1[nH]c2ccccc2c2cc(cc(Nc3ccccc3)c12)-c1cccs1

InChI Key InChIKey=VMXUNHJFSNCZRR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562666   

Target72 kDa type IV collagenase(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562666(CHEMBL4758787)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of recombinant human MMP2 (110 to 452 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in yeast expression system as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562666(CHEMBL4758787)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant human MMP8 (99 to 269 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562666(CHEMBL4758787)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of recombinant human MMP9 (107 to 449 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562666(CHEMBL4758787)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of recombinant human MMP13 (104 to 274 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed