BDBM50562646 CHEMBL4758337

SMILES NC(=O)c1cccc2cc(oc12)C(=O)N1CCN(CC1)c1nc(nc(n1)-c1cnc(N)cc1C(F)(F)F)N1CCOCC1

InChI Key InChIKey=NBUIWUDKADDAKC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562646   

TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562646(CHEMBL4758337)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50562646(CHEMBL4758337)
Affinity DataIC50: 40nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562646(CHEMBL4758337)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50562646(CHEMBL4758337)
Affinity DataIC50: 40nMAssay Description:Inhibition of PI3K-alpha (unknown origin) incubated for 40 mins in presence of ATP by ELISAMore data for this Ligand-Target Pair
In DepthDetails
PubMed