BDBM50562610 CHEMBL4779022

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCNC(=O)CCc2ccc(c(C)n2)-c2cnc(NCc3c4CCOc4ccc3F)n3cnnc23)C(C)(C)C)cc1

InChI Key InChIKey=CQSOTYMFUWTIIR-UHFFFAOYSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562610   

TargetPolycomb protein EED(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50562610(CHEMBL4779022)
Affinity DataKd: <1nMAssay Description:Binding affinity to human N-terminal His6-tagged/thrombin cleavage site fused/ AVI-tagged EED (1 to 441 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50562610(CHEMBL4779022)
Affinity DataKd:  1nMAssay Description:Binding affinity to EED (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolycomb protein EED(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50562610(CHEMBL4779022)
Affinity DataKd:  0.537nMAssay Description:Binding affinity to human N-terminal His-6 tagged EED expressed in Escherichia coli strain BL2(DE3) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolycomb protein EED(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50562610(CHEMBL4779022)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human N-terminal His-6 tagged EED expressed in Escherichia coli strain BL2(DE3) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed