BDBM50562546 CHEMBL4781093

SMILES Fc1ccc(cc1)-c1ccc(OCCCN2CCN(CC2)c2ccncc2)cc1

InChI Key InChIKey=FRXKBKSVWAOOCI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562546   

TargetHistamine H3 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50562546(CHEMBL4781093)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]UR-PI294 from human SP-FLAG-tagged H3R expressed in HEK293T cells measured after 60 to 120 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50562546(CHEMBL4781093)
Affinity DataKi:  3.69E+3nMAssay Description:Displacement of [3H]mepyramine from human H1R expressed in Sf9 cell membranes co-expressing RGS4 measured after 60 mins by scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50562546(CHEMBL4781093)
Affinity DataKi:  7.46E+3nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in Sf9 cell membranes measured after 60 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50562546(CHEMBL4781093)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]histamine from Gialpha2/Gbeta1gamma2-coupled human H4R expressed in Sf9 cell membranes measured after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed