BDBM50562503 CHEMBL4758479

SMILES NS(=O)(=O)NCCNC(=O)c1n[nH]nc1-c1ccc(F)cc1

InChI Key InChIKey=WWVNJUSZTOATIN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50562503   

TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562503(CHEMBL4758479)
Affinity DataIC50: 92nMAssay Description:Inhibition of human N-terminal His-tagged IDO1 expressed in Escherichia coli M15 incubated for 1 hr by UV-Vis spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562503(CHEMBL4758479)
Affinity DataEC50:  74nMAssay Description:Inhibition of human IDO1 in IFN-stimulated human MDA-MB-231 cells preincubated for 48 hrs followed by L-tryptophan addition and measured after 5 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed