BDBM50562502 CHEMBL4749635

SMILES NC(=O)c1n[nH]nc1-c1ccc(F)c(F)c1

InChI Key InChIKey=DHWQXMKOVSPSKI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50562502   

TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562502(CHEMBL4749635)
Affinity DataIC50: 110nMAssay Description:Inhibition of human N-terminal His-tagged IDO1 expressed in Escherichia coli M15 incubated for 1 hr by UV-Vis spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562502(CHEMBL4749635)
Affinity DataEC50:  74nMAssay Description:Inhibition of human IDO1 in IFN-stimulated human MDA-MB-231 cells preincubated for 48 hrs followed by L-tryptophan addition and measured after 5 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562502(CHEMBL4749635)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant N-terminus 6-His tagged IDO1 expressed in Escherichia coli M15 incubated for 1 hr by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed