BDBM50562343 CHEMBL4800181

SMILES CN(C)C(=O)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3cc(CN4CCN(CC4)S(C)(=O)=O)cn3n2)cc1

InChI Key InChIKey=PJHFDUVFAPTIMP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50562343   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50562343(CHEMBL4800181)Copy SMILESCopy InChI

Affinity DataIC50: 68nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
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