BDBM50562342 CHEMBL4756074

SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(nn3c2)-c2ccc(NC(=O)Nc3ccc(F)cc3)cc2)N2CCOCC2)CC1

InChI Key InChIKey=ZOEXBICCWJEIHU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50562342   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50562342(CHEMBL4756074)Copy SMILESCopy InChI

Affinity DataIC50: 105nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
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