BDBM50562069 CHEMBL4785595

SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](CC=C)C(=O)NO)C(C)(C)C

InChI Key InChIKey=DDRBOOUOUSFWET-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562069   

TargetInterstitial collagenase(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50562069(CHEMBL4785595)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PMA-induced human skin fibroblast derived MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50562069(CHEMBL4785595)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of TNF-induced MMP2 isolated from human HT-1080 cell medium by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50562069(CHEMBL4785595)
Affinity DataIC50: 10nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50562069(CHEMBL4785595)
Affinity DataIC50: 11nMAssay Description:Inhibition of human MMP7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed