BDBM50562068 CHEMBL4791227

SMILES CNC(=O)[C@H](Cc1ccc2CCCc2c1)NC(=O)[C@H](CC(C)C)[C@H](CC=C)C(=O)NO

InChI Key InChIKey=MHQJDNZHPIZRRV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562068   

TargetInterstitial collagenase(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50562068(CHEMBL4791227)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of PMA-induced human skin fibroblast derived MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50562068(CHEMBL4791227)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of TNF-induced MMP2 isolated from human HT-1080 cell medium by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50562068(CHEMBL4791227)
Affinity DataIC50: 12nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50562068(CHEMBL4791227)
Affinity DataIC50: 11nMAssay Description:Inhibition of human MMP7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed