BDBM50560851 4-Hydroxyevodiamine::CHEMBL2171794

SMILES CN1C2N(CCc3c2[nH]c2ccccc32)C(=O)c2c(O)cccc12

InChI Key InChIKey=BKYCMCVWWVNOOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50560851   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50560851(4-Hydroxyevodiamine | CHEMBL2171794)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human PDE5A1 (535-860 residues) expressed in Escherichia coli BL21 incubated for 15 mins using [3H]-cGMP as substrate by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed