BDBM50560468 CHEMBL4786529

SMILES Cc1cc(-c2cnc3cc(ccn23)-c2ccc(cc2)N2CCNCC2)c2cc(F)cc(F)c2n1

InChI Key InChIKey=RUBWYYYEDDAWLB-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50560468   

TargetActivin receptor type-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: 32nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: 309nMAssay Description:Inhibition of human ALK1 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetActivin receptor type-1B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: 596nMAssay Description:Inhibition of human ALK4 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human ALK5 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: 41nMAssay Description:Inhibition of human ALK6 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human BMPR2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: 171nMAssay Description:Inhibition of human TGFBR2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of human KDR using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed