BDBM50559936 CHEMBL4744046

SMILES [H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]([H])(N(C2)C#N)c1[nH]c2ccccc2c1CCn1cc(nn1)-c1cccc(Cl)c1

InChI Key InChIKey=ZNXVYSTWUAFJFS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50559936   

TargetC-C chemokine receptor type 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50559936(CHEMBL4744046)
Affinity DataIC50: 8.30E+3nMAssay Description:Antagonist activity at human CCR3 expressed in CHO-K1 cells by PathHunter beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50559936(CHEMBL4744046)
Affinity DataIC50: 7.29E+3nMAssay Description:Antagonist activity at human CCR8 expressed in CHO-K1 cells by PathHunter beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCX3C chemokine receptor 1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50559936(CHEMBL4744046)
Affinity DataIC50: 8.47E+3nMAssay Description:Antagonist activity at human CX3CR1 expressed in CHO-K1 cells by PathHunter beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50559936(CHEMBL4744046)
Affinity DataIC50: 7.94E+3nMAssay Description:Antagonist activity at human CXCR4 expressed in mouse C2C12 cells by PathHunter beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50559936(CHEMBL4744046)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at HTR2C in human U2OS cells by PathHunter beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed