BDBM50559917 CHEMBL4791135

SMILES CC#CC(=O)Nc1cc2c(Oc3ccc(cc3)C(=O)Nc3ccccn3)ccnc2cc1OC1CCOCC1

InChI Key InChIKey=GLHXUKWUPVVWIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559917   

TargetEpidermal growth factor receptor(Human)
Acerta Pharma

Curated by ChEMBL
LigandPNGBDBM50559917(CHEMBL4791135)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) expressed in baculovirus system using fluorescein labeled PDGFR-tide substrate peptide preincubated for 60 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

Curated by ChEMBL
LigandPNGBDBM50559917(CHEMBL4791135)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged BTK expressed in baculovirus infected Sf9 cells using fluorescein labeled Blk/Lynt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed