BDBM50559915 CHEMBL4796130

SMILES CCN1CCN(CC#CC(=O)Nc2ccc3nccc(Oc4ccc(cc4)C(=O)Nc4ccccn4)c3c2)CC1

InChI Key InChIKey=XQTAXOFEPGOWGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559915   

TargetEpidermal growth factor receptor(Human)
Acerta Pharma

Curated by ChEMBL
LigandPNGBDBM50559915(CHEMBL4796130)
Affinity DataIC50: 55nMAssay Description:Inhibition of EGFR (unknown origin) expressed in baculovirus system using fluorescein labeled PDGFR-tide substrate peptide preincubated for 60 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

Curated by ChEMBL
LigandPNGBDBM50559915(CHEMBL4796130)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged BTK expressed in baculovirus infected Sf9 cells using fluorescein labeled Blk/Lynt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed