BDBM50559821 CHEMBL4781596

SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1

InChI Key InChIKey=OQDKZJYHCUFKRI-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50559821   

TargetN-formyl peptide receptor 2(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559821(CHEMBL4781596)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559821(CHEMBL4781596)
Affinity DataEC50:  280nMAssay Description:Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetFormyl peptide receptor 2(Mouse)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559821(CHEMBL4781596)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559821(CHEMBL4781596)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed