BDBM50559593 CHEMBL4740734

SMILES Cc1cc(\C=C2/SC(=O)NC2=O)c(C)n1-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ORQKDFNKRPPNAB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50559593   

TargetBile acid receptor(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50559593(CHEMBL4740734)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed