BDBM50559493 CHEMBL4793741

SMILES Oc1cc(cc(O)c1-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)c1cccs1

InChI Key InChIKey=ZVLXZKPJQVEUKM-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50559493   

TargetCannabinoid receptor 2(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50559493(CHEMBL4793741)
Affinity DataEC50:  676nMAssay Description:Inverse agonist activity at human recombinant cannabinoid CB2 receptor expressed in HEK cells transfected with CNG assessed as increase in cAMP level...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50559493(CHEMBL4793741)
Affinity DataEC50:  1.29E+3nMAssay Description:Inverse agonist activity at cannabinoid CB2 receptor in human U2OS cells assessed as induction of beta-arrestin recruitment using CCF4/AM as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50559493(CHEMBL4793741)
Affinity DataKi:  187nMAssay Description:Displacement of [3H]-CP55940 from human recombinant cannabinoid CB2 receptor expressed in HEK cell membranes incubated for 1.5 hrs by liquid scintill...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50559493(CHEMBL4793741)
Affinity DataKi:  3.74E+3nMAssay Description:Displacement of [3H]-CP55940 from human recombinant cannabinoid CB1 receptor expressed in HEK cell membranes incubated for 1.5 hrs by liquid scintill...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed