BDBM50558019 CHEMBL4777614

SMILES COc1cc2C=NCCc2cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=TVABXPHWPOLVTC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50558019   

TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50558019(CHEMBL4777614)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of ALK (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50558019(CHEMBL4777614)
Affinity DataIC50: 39nMAssay Description:Inhibition of crizotinib-resistant ALK L1196M mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed