BDBM50557837 CHEMBL4753950

SMILES O=C1CC(NCc2ccco2)C(=O)NN1

InChI Key InChIKey=MDESMYPAACPJGO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557837   

TargetRNA demethylase ALKBH5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557837(CHEMBL4753950)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of ALKBH5 demethylase activity (unknown origin) assessed as increase in methylated 6A-RNA level incubated for 2 hrs by colorimetric analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetRNA demethylase ALKBH5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557837(CHEMBL4753950)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of recombinant ALKBH5 (unknown origin) mediated demethylase activity using methylated N6-adenine RNA probe with CUUGUCAm6ACAGCAGA sequence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed