BDBM50557761 CHEMBL4758580

SMILES COc1cn2ncc(-c3ccnc(OC(C)C)c3)c2nc1-c1cnn(C)c1

InChI Key InChIKey=WGIIRAICDHPHBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557761   

TargetTGF-beta receptor type-2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50557761(CHEMBL4758580)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetActivin receptor type-2A(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50557761(CHEMBL4758580)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of ACVR2A (unknown origin) using biotin- labelled KTLQDLVYDLSTSGSGSGLPLFVQRTVART substrate in presence of [gamma33P] ATP measured after 20...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed