BDBM50557695 CHEMBL4742889

SMILES COc1cc(OC)c(Cl)c(COc2cnc(Nc3c(C)cccc3NCC=O)nc2)c1Cl

InChI Key InChIKey=JOHIKBITJWWHQQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50557695   

TargetFibroblast growth factor receptor 4(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50557695(CHEMBL4742889)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human His-tagged FGFR4 (781 to 1338 residues) cytoplasmic domain expressed in baculovirus expression system using Tyr 04 pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50557695(CHEMBL4742889)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human His-tagged FGFR1 (308 to 731 residues) cytoplasmic domain expressed in baculovirus expression system using Tyr 01 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50557695(CHEMBL4742889)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human His-tagged FGFR2 (403 to 822 residues) cytoplasmic domain expressed in baculovirus expression system using Tyr 04 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50557695(CHEMBL4742889)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human His-tagged FGFR3 (399 to 806 residues) cytoplasmic domain expressed in baculovirus expression system using Tyr 04 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed