BDBM50557486 CHEMBL4747506

SMILES CC#CC(=O)N1CCC[C@@H]1c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12

InChI Key InChIKey=WDENQIQQYWYTPO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50557486   

TargetTyrosine-protein kinase BTK(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50557486(CHEMBL4747506)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of BTK (unknown origin) One-hour enzymatic assay with pre-incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50557486(CHEMBL4747506)
Affinity DataIC50: 101nMAssay Description:Inhibition of human BTK using poly-Glu-Tyr (4:1) as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50557486(CHEMBL4747506)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged human EGFR (668 to 1210 residues) expressed in baculovirus expression system using poly-Glu-Tyr (4:1) as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed