BDBM50557190 CHEMBL4796520::US12030867, Compound 4d

SMILES CCCc1cc2cc(cc(N[C@H]3CC[C@H](O)CC3)c2c(=O)[nH]1)-n1nc(C)c2c1CC(C)(C)CC2=O

InChI Key InChIKey=QRUAXSIQUFUVJC-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50557190   

TargetHeat shock protein HSP 90-beta(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50557190(CHEMBL4796520 | US12030867, Compound 4d)
Affinity DataIC50: 40nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-beta incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50557190(CHEMBL4796520 | US12030867, Compound 4d)
Affinity DataIC50: 886nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-alpha incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50557190(CHEMBL4796520 | US12030867, Compound 4d)
Affinity DataKd:  886nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-beta(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50557190(CHEMBL4796520 | US12030867, Compound 4d)
Affinity DataKd:  40nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent