BDBM50556949 CHEMBL4745420

SMILES ONC(=O)Cc1ccc(OCCCn2c3CNCCc3c3cccc(Cl)c23)cc1

InChI Key InChIKey=LVBRBYYFSGTCAR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50556949   

TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50556949(CHEMBL4745420)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of human HDAC1 pre-incubated for 5 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50556949(CHEMBL4745420)
Affinity DataIC50: 459nMAssay Description:Inhibition of human HDAC6 pre-incubated for 5 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50556949(CHEMBL4745420)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed